You don't mess with the dynamic in lives of ageless characters; unless they're losing their relevance and you need something sensational to pick things up again... which may be what's happening with Archie. Growing up I was addicted to these and was once even told off my the librarian at a local private library for hanging around the section where those books were for too long. I sometimes just read the books right there standing instead of bothering to check them out.:)
My bet though is that this will never really happen and it'll be some sort of "what-if" kinda thing that they've done a bunch of times.
For the record though, I vote for Betty. :)
Update: Looks like I was right about the "what-if" part.